You know, so that's a big concern. So, you know, there's there certainly, I think, a good hypothesis to be made that potentially, you know, one or two of these common cold viruses, could the antibodies you make against them could also somehow maybe, maybe, you know, interact with the sars-cov-2 virus, potentially neutralize it? So I showed him. Yes. I mean, my mom, my mom and my dad, I got my whole family. Yeah. Vitamin D3 I monitor that are offering. Ninety proof Franklin County, Kentucky, Buffalo Trace, American family owned and fiercely independent. That's it. But I got to have, you know, more time with my son. So he doesn't believe in you can't wear like swimsuits or anything in this on him. I know. Two hundred milligrams. I'll have one sent to you. And, you know, if they're not getting enough sun, they're not getting enough sun because people stay inside, more people stay inside. But TMJ is, what am I saying, the right thing. There's been studies African-Americans are severely deficient. But also maybe that is not feeling well because vitamin D deficiency plays a factor in that as well. Like if there's if there's antibodies that you're making against another coronavirus, beta coronavirus that's in the same family as this SARS one, no one's had SARS, one in the United States, you know, so like that one doesn't that that's not as relevant as. The ones that you plug in. And at that point I, I was like looking through everything on my toiletries and everything, like, what do I have to get rid of what's in there that could be harmful and smells like fluoride like in my toothpaste. I don't like your door asking me like six months ago or more, you know, but. And he was that this guy was in the military. For this reason, she made a special appearance in 2020 on the Joe Regan podcast to discuss the link between the severity of COVID-19 and low levels of vitamin D. She quoted a meta-analysis appearing in the British Medical Journal regarding 25 different randomized controlled trials. Absolutely. I mean, so far the maximum I've seen measured is like 70 times that your blood can get 70 times 200 say I was like, wow, 18000 or 17000 or something. Well when I do squats for sure, any time I do lunges and squats and heavy leg days, I'm a zombie for two days and like if I have a particularly intellectually challenging podcast I'll skip leg days because I know I'm just going to be too stupid. Oh, like crazy. So Class Kov one, the virus that was responsible for the original SARS outbreak in 2002 or something, the Mars One in the Middle East. Oh, my son doesn't want to take he doesn't want to sleep ever. By the way, the studies were with gum, not the toothpaste. There's a reason why I want to talk about this. Ropin. Does it help, does it help your sleep. Oh we did. Yes. Then I was put in a bunch of water on a nose breathing big, long, deep nose. It's really good. Thank you, Ron. They're not just making whiskey. I was like, I'm killing you bitches and killing all you dirty viruses. So I have the friend is the friend. I mean I guess eventually I was doing we were in there, I was in there for I don't know how long and then I'd go in the ice and then go back in there but I would get out and I would collapse. So that was the Philippines. We were doing a cleaning, you know, dental hygiene thing. Rate your immune system and strengthen it is important. What are you talking about. You wear this. And I totally stopped having for the most part, Dan says, yeah, like I went through one episode where what happens when someone has a nightmare is like if someone else in the sharing the bed with you, like, tries to stop you or help, like because I'm still asleep, I'm not aware that that's my husband doing that. I'll find you know al-Thani and see I was looking for my LPT but I was out because that like helps Karmiel. It monitors the temperature of the meat. They both have been shown to increase lymphocyte numbers and also like other milit cells and stuff in people. Cloudy all the time. And when he was talking about after the fact, what Michael was talking about was how that is proven to be correct in New York and that some monstrous number, like 80 percent of the people put on ventilators wound up dying, not just New York. The bottom line is each individual must decide for themselves what is best for their life. They have produced more than two million liters of hand sanitizer so far, and they're still making bourbon as well, rolling it more barrels into the warehouses every day. Please give it up for the great and powerful Dr. Rhonda Patrick Girlyman podcast, The Joe Rogan Experience, trained by day Joe Rogan podcast, My Night All Day. I think it's real. Well I would wonder and I know there's there's supposedly some sort of Harvard study that's ongoing right now measuring all sorts of markers in people that have done hot yoga and whether or not it mimics heat, shock proteins that are created in the sauna. But sometimes you've got to like, look at the full body of data. And I got that fucker right. People are starving. And it's totally putting me as calculating as asleep. It's for the lung function in the respiratory function. So it's not like a hard core quantitative biomarker which is so badly needed. I think that's going to make a big difference and test. No no no no. Like humidity, like the higher the more humid, the better that was. And he shows the X-rays and he shows me before and after. And that actually potentially could bind sars-cov-2 virus and prevent it from it's like sequestering it, preventing it from entering the cell. Joe Rogan & Dr. Rhonda Patrick Discuss Their Vitamin D Supplement Regimens - YouTube 0:00 / 1:26 Joe Rogan & Dr. Rhonda Patrick Discuss Their Vitamin D Supplement. I bet you was the same because they like do the same protocol and this was like to 10 or to 20. Right. It makes your breath smell worse. I really think you are awesome to talk to. And doctors, they varied in how they approached it. Particularly after hot yoga. I love this thing because you wear a belt and the weight is actually pull. Man, I think you've got to have the option. So before there was ever a real America. Right. I think the first time I came on your podcast, like, I know many years, it's been it's been a while, but I talked about this on years. I don't stop at all. He will. So it's like it's having it's not something that like necessarily needs to be done all the time. Right? I hope you got some good information on this. I don't I think that I think what you don't want to just speculate? By one point eight years. And it's been shown that like if you for example, if you give mice lipo polysaccharide or something that's going to cause lung injury and then you give them vitamin D for the lung injury itself also causes the E receptor to decrease. And so, yeah, I have some grey hairs, it grey hairs. So I'm doing like popcorn. They know because they taste it all. And she, like my friend, is a little bit you know, she's a little bit of a skeptic when it comes to, like vitamins or anything like that, you know, so I wasn't going to say anything because her and I have gone and so on. But it's not something that I'm certain that people need to do on a daily basis. It's far infrared and they use it. So it's been the Spike region and it's a aspartame to glycine mutation. We're also brought to you by Buffalo Trace Whiskey, Buffalo Trace Whiskey is the oldest company I've ever even heard of. I love their rubs, their Saskatchewan blackened rub. One eighty, one eighty is great. But, you know, I'm not a physician and medical doctor. The problem is, is that that's not like it's going to be a short lived protection, like it's going to be it's not like you can it's not like a vaccine where your body's making its own antibodies and they're and they're more longer lived, you know. Like there's huge variations in the results and it all really seems to come down to dose like it really does. Lifting weights increases bone density, tendon strength, so many different variables that are so huge because as your body gets older, those are the things that go south. And I learned so much as I always do. I'm confident that's a very common phenomenon. I'm like, I wonder what this is doing if I click cause but the lack of sleep because he would wake up like I would be getting interrupted multiple times at night, like, you know, where it was like I don't know, he was going through some developmental stage and and he would stand in his crib and it's like so I was I was getting woken up multiple times at night for like prolonged periods, very, very like fragmented sleep. There was less this. and she has reactive airways. Cause there's so many studies published. And then there's two different ones that are responsible for the common cold. Maybe that's why they're shittier, you know? So a subjective measurement would be a clinical clinical person, like measuring a whole battery of things they do. Pressure is in Tarzana. And I haven't done the research, you know, and it goes he comes in and he goes, I've never seen this before, but your cavities are gone. It's associated with high blood pressure, heart attacks, the risk of all sorts of ailments. I went to the dentist. It changes everything. It doesn't do anything to the two receptor levels. Asymptomatic. And like like he had been reading some studies to confirm that. So many debates about it. So, like, I think that's really important from bright light exposure is just there's just study after study showing it sets your circadian clock boom. But anyways, you give them this amyloid beta and after like a couple of days, they become paralyzed or they're like laying in their little petri dish plate on the cold food. Without good health, it is incredibly difficult if not impossible to revel in the joy of life. But where yeah. But like adults, you know, you know, I think that if you're working, you want to open your your your restaurant back up your, you know, like masks. What kind of a timeline do you think they have for something like this? That thing will go to like one sixty five like just from like you know, just from the corn, just from the popcorn milk. And so it's part of the adaptation process as well, you know, being able to handle the heat stress. It's bad for you and it's bad for your spouse. It gets gets grosser meditation. You know, it's well, it's it's important. Like you're. You're hanging by your ankles and decompressing your spine. But the fact that it has been shown to to treat to improve sepsis outcomes in multiple, you know, studies. No kaat why. Like right above my above. You should only do these activities alone or with members of your household. What are the what are the methods you can use to help boost your immune system, keep your body healthy? The people with low baseline vitamin D levels. I mean, New York City got hit pretty hard, but, you know, we have been on lockdown, so that has to be accounted for. So it totally messes the immune system up. There's an sciatica is is a nerve that comes from your spine right here. We have some here. I was like, I think I'm fucked myself up here. Popcorn. I'll show it to you. So, I mean, that's. We had to like there was some weird fire thing. I mean, you know, vitamin D is something, again, like 70 percent of the US population has insufficient levels. Yeah, I'm hoping that the accuracy of the PCR test improves. You want do you if you're looking at your screens, do you use blue light blocking glasses? Whiskey magazine named the best distillery in America again this year. Wow. So you keep looking down. That company got a lot of shit for their claims. I have like I've been to to Rick Rubin's house and we've done like it was like 200 and something. And if you need to speak to an attorney there, independent attorney network is there to guide and advise you. There's interesting studies that have shown, you know, like that the intravenous vitamin C is like dramatically reducing inflammation as well. Providing anti-inflammatory effects Did I ever tell you my crazy story, fun story about this crazy story? Like if you have a herniation of the disc or if you have a bulging disc, it's pushing against your nerve. So I'm like wondering when do I when can I cut the nap out? Well, we, we had ours done just a few months before. I told him, I'm like, I'm going to do some reading research and see if I can find, you know, if there's any, you know, possibility that don't have to, like, get a filling. Trager and the Trager Day Sale goes from May, May 15th, which is tomorrow to well, you'll get this today, May 15th, May 17, 20 percent off all Rob's sauces and liners. So monoclonal antibodies, I think, are a really big, you know, possibility for a promising therapeutic because you can then I mean, the problem is growing like large scale manufacturing them. I don't know if they did. I mean, that's a big open question that seems possible without we don't have an answer to that. So, like, if you can identify these antibodies and then manufacture them, you can inject them in people and then potentially get some protection. You could do everything on it. So there have been there have been quite a few studies looking at children that are asymptomatic, children that have mild symptoms and children that are symptomatic. What difference? And then and then putting them in a place where they can't get any vitamin D from the sun. June 21st 2020 92000 shitheads who have half assed their whole life. So what we did, I went I visited the Sauna Society, and it was in November, it was cold and it's right on a lake. And I know that the vaccine people that are working on vaccines are working on them. So, like like I understand what it's like to not have a sauna and to have to use hot bath. And those people are more likely to die from respiratory infections just based on that gene alone. I'm not sure I when the whole thing started, when the lockdown started, I was getting the sauna really hot. This alleviates suffering and then puts the body in homeostasis. Also, as the oldest continuously operating distillery in America, Buffalo Trace Distillery has experienced more than its fair share of adversity floods, fires, wars, recessions and prohibition. So, you know, the thing with monoclonal antibodies is they're a little more specific because, you know, they neutralize and you're like growing them up like you've done all that test as opposed to just letting your immune system do its thing. I got a mouthpiece and it's amazing. I don't know if it was like placebo or not, but like B 12 is a big impact on your ability to do work. So there's one that cross reacts with the Sajko, one which has a very it's very the sequence is very homologous to sars-cov-2 virus. You're having your discs or protruding and your disc. I forgot the the duration, but they're you know, they they were much less likely to come down with the common cold. Right. No matter what happens, you want to make sure that your loved ones are protected. But it shouldn't be you shouldn't be scared to do it because that's what's going to protect that area. Oh yeah. So you mean by how many times you've caught the flu, how many times you've whether you're actually going to it, how you respond to it, you know? So that's a marker a month. You don't use this on those occasion. Just constant wear for years then. I get out of here. It's been like just having having the effect. But how long would you say short lived? But can you measure he talks about team the bath versus. April 19th 2020 It would be so scared. Well, oh, no. RELATED: Dr. Rhonda Patrick's Fish Oil Protocol And I think that that I think that eventually there's going to be therapeutics that are identified, you know, not multiple ones maybe. So there's been a meta analysis looking at of twelve different studies, I think where vitamin K one or vitamin K two were given and both of those improved bone mineral density and prevented any hypoglycemia, because when you take vitamin D, you absorb calcium better like something crazy, like 40 percent more dietary calcium is being absorbed. Wow. The most recent guest on the hugely popular The Joe Rogan Experience is Rhonda Patrick PhD, a cell biologist whose work focuses on promoting a healthier, longer lifespan. The I think the entire disease, it's out of their system. And so like I mean, you're breathing like it's like burning you. But I think that's also a really good I mean, there's a ton of theories. But, man, you know, I think just like got the guy's house I was doing and I was trying to impress them. Conducting regular blood testing is important because levels of vitamin D can be too high. Dr. Rhonda Patrick is a Ph.D in biomedical science and expert on nutritional health. I take vitamin D. I certainly don't know if it's going to prevent covid-19, but I'm not hoping it does. Well, the ones in my multi so I don't buy vitamin K one is really it's found in dark leafy greens. And I just I don't know. So, you know, it's kind of like correlation. You have to you can't you can't do this, especially given one option. And it's been shown that that Vonne Gillibrand factor also isn't like is higher. Yeah. Of course I'm nursing him. There is some non-human primates studies that that did that and also animal studies as well. Yeah. And what dose for one. RELATED: Dr. Rhonda Patricks Fish Oil Protocol. Popcorn will spike it really bad. So why do you take five. So yeah, there's a hot Basar like the only the only really choice if you don't have a hot sauna, no pomes on it. I'll send it to you. They have been distilling whiskey since seventeen seventy three people and they've been named this year. Yeah, I mean, so there are some there's potential biomarkers being identified to react to protein being one inflammation. That's not UVB. And then so elderly elderly are like insanely more deficient. Yeah. Yeah, he had us do this like there was like two tents and and it was a conference that I gave a talk at. That makes a huge impact on my son and his sleep cycle, like because children are really sensitive to light because they don't have like cataracts and stuff. It's a big I really because of you I take 5000. So the upper the tolerable upper intake has been set by the Nutrition Board, the Institute of Medicine, to be 4000 hours a day. So they're not as healthy, they're not as physically active and not whatever, even though those confounding factors are usually corrected for it's old. And I freak out and I scream. It is. But once you get yourself down, you just relax and all of your weight, see how other guys doing it. Distilled, aged and bottled by Buffalo Trace Distillery 90 Proof. Yeah, a lot. From the App Store or the Google Play store today, make sure you use the referral code, Joe Rogan, all one word, you will receive ten dollars and the cash app will send ten dollars to our good friend Justin Ren's fight for the forgotten charity building wells for the Pigmies in the Congo. I think sanitising making sure you're using hand sanitizer and cleanliness and all the good stuff. Hopefully people are going to start looking at the vitamin D. I really like that. So this is also a problem with vaccines. That's cool. Plus you're just not sleeping enough. They're never going to forget how weird this is to do in all their classrooms on iPads. I love that giant. Like what are the causes? I mean, there are those people to. Look, I went a long time without Asthana. You should when they start to go there, I'm like, you should have a hard time and you should judge. So I really I just I really you imagine if vitamin D really did help, like if if there was something that could be given along with the other stuff from DV or whatever, whatever, it's going to be the stuff that we identify, but like vitamin D so, so cheap, it's so easy and so many people are deficient and insufficient, you know, like so yes. I got ten bottles of water and I just pouring bottles of water because it was just me in there. But you know what, I'm talking. How other health factors, you know, and but there was a big study just released not long ago from from like the National Office of Statistics in Britain or something like that. They're not as sore. So so this is like there's one thing that it's important to keep in mind when we say asymptomatic, like, you know, there's asymptomatic and like a person that never actually gets symptoms. Podcast Notes is a Signal From the Noise LLC Production, All Right Reserved, Berkshire Hathaway Annual Shareholders Meeting, Christopher Lockhead's Follow Your Different, Everyday Espionage Podcast with Andrew Bustamante, Feel Better, Live More With Dr. Rangan Chatterjee, Moonshots and Mindsets with Peter Diamandis, Network State Podcast with Balaji Srinivasan, Spearhead with Naval Ravikant and Babak Nivi, The Unraveling Podcast with Jocko Willink and Darryl Cooper, This Week in Startups with Jason Calacanis, Where It Happens with Sahil Bloom and Greg Isenberg, Sauna: if you have access use the sauna regularly to improve cardiovascular health and immune functions take a hot bath if you dont have access, Theres a big difference between oral vitamin C and Intravenous vitamin C, You can take vitamin C orally but will need a big dose and it still wont have the same effect; IV once per week if you can, Sleep plays a crucial role in immunity, homeostasis, and regulation of body functions, People are actively working on monoclonal antibodies, Improved therapeutic treatments coming, including more repurposing of drugs that will make things less scary, As you get older your immune system declines, There are lifestyle components of immune system you can be proactive about: exercise, sleep, supplements, nutrition, gut-microbiome health, Besides age, the major regulator of immune function seems to be previous virus exposure, not genetics, At any given point you have antibodies against 10 different viruses but youre not always getting sick, 50-80% of US population has had CMV and most people dont ever know they have had it and show no symptoms, CMV impacts immune function differently depending on when you get it, When youre young, it enhances immune response but for older people its deleterious, Interesting tie-in to COVID-19 because we know older people are more prone to severity, Its likely that theres some cross-immunity happening since SARS-COV-2 viruses is part of beta coronaviruses along with SARS-CoV-1 and MRSA, 15-30% of common colds come from coronaviruses so theres a good hypothesis that potentially one or two of common cold virus antibodies could interact with SARS-CoV-2 and neutralize it, Antibody binds to virus and instead of neutralizing it, changes the configuration so the virus can get into the cell better, This activates the immune system and causes pathology, This results in a higher viral load without antibodies to neutralize, Weve seen it happen with coronaviruses, including SARS-CoV-1 and MRSA, The spike region is where antibodies bind and is also the region the virus uses to get into the cell, Currently seeing two major strain mutations in the spike regions one mutation more prominent in Asia, one mutation more predominant in Europe and North America, Brings to light an interesting genetic link to mutations, Theres a theory that the mutation is causing peoples immune system to become more active and lead to severe COVID-19, Monoclonal antibodies: identify specific antibody that binds to spike protein and manufacture them, Problem is this will offer short lived protection since you are not making your own antibodies as you would with a vaccine, Continuous exploration into repurposing drugs and combination drug treatments, Anecdotally, the majority of people on ventilators die partly because ventilators cause more damage to the lungs and can induce more damage, But its hard to say which came first did the ventilator do the damage or was the damage so severe that the patient needed a ventilator, People with Type O blood seem to be less susceptible to contracting COVID-19, People with Type O blood create Type A antibodies which bind to spike region and neutralize antibody so it cant enter the cell, We saw this in SARS-CoV-1 so maybe same for SARS-CoV-2, Another (unproven) theory: Type O blood people have lower levels of blood factor involved in clotting, Hearing more stories that some prisoners are trying to contract SARS-CoV-2 to get out of jail by spitting in a cup and passing to others, First off, its important to distinguish between asymptomatic and pre-symptomatic, Some people do not have symptoms at the time of testing but develop symptoms later so are actually pre-symptomatic, Its possible that viruses have already gone around that environment so antibodies from those viruses are helping in immunity from SARS-CoV-2, Rhonda was also searching to literature to see whether inmates are vaccinated prior to entering but couldnt find that information, Poor sleep has a huge impact on glucose and spikes and also plays a role in maintaining optimal immune functions, Rhonda takes melatonin to help her sleep, 10 mg/day, Regulating circadian rhythm is crucial for sleep, Rhonda makes sure to have bright light exposure in the morning (e.g., opening curtains, walking outside), and changes the lighting in the house in the evening to red lights, 70% of US population has insufficient Vitamin D levels; 28% are deficient, Body can generate naturally when exposed to sun daily, Obese people in US are also more likely to be vitamin D deficient, Genetic polymorphisms: people that have variations in genes that cause them to have less vitamin D, These people are more likely to die from respiratory infection, African Americans in the US are 28x more deficient in vitamin D than Caucasians, A recent study that looked at COVID-19 patients observed an inverse relationship between vitamin D levels and COVID-19 symptoms: the lower the vitamin D levels, the higher the severity of COVID-19, In Indonesia almost all patients that died from COVID-19 were vitamin D deficient, Melanin blocks ability to produce Vitamin D, In the US and Europe, African Americans and black people are more likely to die from COVID-19, Even when adjusting for SES and lifestyle factors, this was still true so something else must be happening, Tolerable upper intake is 4000 IUs per day but its best to get vitamin D blood test to measure levels, There are clinical studies exploring the role of vitamin D but not many in the US, Rhonda wants to see nurses and first responders take vitamin D to see the role in prevention but those studies are not being done, Joe uses the sauna 7 days/week, 180-degrees for 25 min, Rhonda uses the sauna 5 days/week, 180-degrees for 25 min, Heart rate variability improves, blood pressure goes down, cardiovascular health improves, all-cause mortality decreases, Sauna use also improves immune system and makes you more resilient against infection, Brain-derived neurotropic factors (BDNF) increases with exercise and heat stress (sauna), The positive benefits of physical activity on the cardiovascular system were enhanced when sauna was added, Sauna use increases heat shock proteins which prevent muscle atrophy, neurodegenerative genes, and have anti-depressant effects, People who sat in 160-degree sauna for 30 minutes had a 60% increase in heat shock protein compared to baseline, Large Harvard study being done to assess whether hot yoga increases heat shock protein, Heat shock protein have antiviral activity against influenza A, Regular sauna is heating ambient air which in turn raises core body temperature, Infrared saunas are directly heating body without heating the ambient air for example, in a heating tent or blanket, We know more about the effects of dry sauna, For people who dont have access to sauna, a hot bath is a good modality for heat shock protein, Studies being done to assess whether sauna can have anti-depressant effect on depressed patients, Saunas could also provide an avenue for giving sedentary and disabled people the benefits of physical activity without exercising, Ice baths and cold showers can be comparable to cryotherapy but you have to stay in the cold water longer, Cold shock protein hasnt really been measured in humans, instead whats measured is norepinephrine which has been shown to increase, Cold shock protein and hot shock protein have been shown to improve mood as well, The pharmacokinetics of vitamin C are very different in oral vs IV consumption, Oral vitamin C is good for immune function, etc. And then potentially, you know, you may have this like non neutralizing antibody that could cause problems. I know it's hard though. I don't know all the specifics of that. I like the ginger lemon a lot and I like this one. This remains true whether the vitamin is obtained from the sun, through foods or supplements. That's untenable. Dr. Rhonda Patrick (@foundmyfitness) has a Ph.D. in biomedical science and is an expert on nutritional health. Getting your vitamin D = less depression. So basically they're all vitamin D deficient, all the ones that are dying. And I hope you got as much out of it as I did. And so as you get older, your your T cell population becomes more focused on fighting that virus and less so on other viruses that you're exposed to.
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